Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150868 | 0.85 | TSHR (0.52) | KEAP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1773099 | 0.82 | HTR2A (0.56) | MEN1KMT2AHPGDKEAP1LMNA | |
| SCHEMBL12869648 | 0.79 | TP53 (0.46) | KEAP1SLC5A1SLC5A2SLC6A2SLC6A4 | |
| SCHEMBL26988103 | 0.79 | KEAP1 (0.44) | MEN1KMT2AKEAP1SLC6A2SLC6A4 | |
| SCHEMBL11299196 | 0.79 | SLC6A2 (0.44) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL560071 | 0.79 | KEAP1 (0.70) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL4869623 | 0.79 | MPO (0.45) | KMT2AKEAP1SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL608449 | 0.79 | PNMT (0.50) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL11631513 | 0.79 | MEN1 (0.43) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL10818489 | 0.79 | MEN1 (0.66) | MEN1KMT2AMAPTCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111997-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL COMPANY, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4007225-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-08 | — | — | US | disclosed |
| US-3953500-A | ANTIPYRETICS, ANALGESICS, ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-27 | — | — | US | disclosed |