Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023654 | 0.78 | HTR1B (0.41) | SIGMAR1HTR2CBCHE | |
| Hydrochloric Acid SCHEMBL6023966 | 0.77 | HTR1B (0.40) | SIGMAR1HTR2CBCHE | |
| SCHEMBL6024115 | 0.77 | SIGMAR1 (0.47) | SIGMAR1NR3C1PGRNR3C2 | |
| SCHEMBL2260650 | 0.74 | HTR2A (0.55) | NR3C1PGRNR3C2ARHTR2A | |
| SCHEMBL1692142 | 0.73 | GABRA1 (0.47) | NR3C1PGRNR3C2ARHTR2A | |
| SCHEMBL1452618 | 0.71 | AHR (0.47) | NR3C1PGRNR3C2ARHTR2A | |
| SCHEMBL2260659 | 0.71 | HTR2A (0.45) | HTR2ABCHEAHR | |
| SCHEMBL593512 | 0.70 | AHR (0.50) | NR3C1PGRNR3C2ARBCHE | |
| SCHEMBL6024171 | 0.70 | TAS1R3 (0.51) | SIGMAR1TAS1R3TAS1R1AHRBACE1 | |
| SCHEMBL6023863 | 0.70 | TAS1R3 (0.39) | SIGMAR1TAS1R3TAS1R1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214859-B1 | PSYCHOLOGICAL DISORDERS; ALZHEIMER'S DISORDERS; PARKINSON'SDISORDERS | FUJIMOTO BROTHERS CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0957080-A1 | NOVEL ETHYLAMINE DERIVATIVES | Fujimoto Brothers Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |