Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RAF1 | P04049 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30871113 | 0.87 | MAPT (0.66) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27967569 | 0.85 | VCAM1 (0.70) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22734863 | 0.85 | CASP6 (0.62) | VCAM1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4343389 | 0.84 | ALDH1A1 (0.66) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4497059 | 0.83 | ALDH1A1 (0.68) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6866237 | 0.83 | VCAM1 (0.62) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL544644 | 0.82 | TSHR (0.68) | ALDH1A1MEN1KMT2AHPGDHSP90AA1 | |
| SCHEMBL239454 | 0.81 | VCAM1 (0.74) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30811551 | 0.81 | VCAM1 (0.74) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9851947 | 0.81 | VCAM1 (0.64) | VCAM1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| CN-1263887-A | Benzimidazole derivative and hair maintaining agent, skin external use agent | SHISEIDO CO LTD (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | VCAM1 1965/4885ALDH1A1 839/4885MEN1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.