Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988146 | 0.93 | GAA (0.51) | SMN1; SMN2LMNAALOX15TSHRPARP10 | |
| SCHEMBL7992360 | 0.82 | ADRA1D (0.46) | SMN1; SMN2LMNATSHRKMT2AGAA | |
| SCHEMBL2145646 | 0.80 | GAA (0.51) | SMN1; SMN2LMNAALOX15TSHRPARP10 | |
| SCHEMBL7988810 | 0.79 | ADORA2A (0.51) | TSHRKMT2AGAAALDH1A1HTT | |
| SCHEMBL7987837 | 0.78 | RECQL (0.47) | SMN1; SMN2LMNAALOX15TSHRPARP10 | |
| SCHEMBL7984250 | 0.77 | PARP10 (0.53) | SMN1; SMN2TSHRPARP10GAAL3MBTL1 | |
| SCHEMBL7974495 | 0.77 | ADORA2A (0.48) | LMNAKMT2AGAAALDH1A1HPGD | |
| SCHEMBL5483136 | 0.76 | PKM (0.59) | LMNATSHRGAAALDH1A1 | |
| SCHEMBL7988227 | 0.76 | TLR8 (0.45) | SMN1; SMN2KMT2AGAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7987445 | 0.74 | PKM (0.57) | LMNATSHRGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |