Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7984737 | 0.98 | ADORA2A (0.47) | ADORA2AGAATLR8LMNAPDE4A | |
| SCHEMBL7988227 | 0.95 | TLR8 (0.45) | ADORA2AGAATLR8PDE4APDE4B | |
| SCHEMBL7985335 | 0.94 | TLR8 (0.44) | ADORA2ATLR8ALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL7974102 | 0.92 | TLR8 (0.46) | ADORA2ATLR8ALDH1A1KMT2ATDP1 | |
| SCHEMBL7985623 | 0.90 | ADORA2A (0.45) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7988189 | 0.83 | ADORA2A (0.42) | ADORA2ALMNAADORA2BALDH1A1ADORA1 | |
| SCHEMBL18050888 | 0.79 | TLR8 (0.42) | ADORA2ATLR8LMNAPDE4APDE4B | |
| SCHEMBL18050894 | 0.78 | TLR8 (0.41) | ADORA2AGAATLR8PDE4APDE4B | |
| SCHEMBL7992360 | 0.78 | ADRA1D (0.46) | ADORA2AGAALMNAKMT2AMEN1 | |
| SCHEMBL3465048 | 0.77 | ALDH1A1 (0.49) | ADORA2AGAATLR8LMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |