Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963673 | 0.80 | SRC (0.30) | SRCBRAFKDR | |
| SCHEMBL6969574 | 0.74 | GABRA2 (0.43) | — | |
| SCHEMBL4658013 | 0.73 | MEN1 (0.41) | MEN1HPGDKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL6055634 | 0.67 | GABRB3 (0.43) | SMN1; SMN2 | |
| SCHEMBL6968437 | 0.67 | HPGD (0.36) | MEN1HPGDKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL16202103 | 0.60 | MAPT (0.47) | MEN1HPGDKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL6104950 | 0.59 | SRC (0.30) | SRCBRAFKDR | |
| SCHEMBL7101511 | 0.59 | GABRA2 (0.43) | — | |
| SCHEMBL6976748 | 0.59 | GABRA2 (0.43) | — | |
| SCHEMBL6866331 | 0.58 | GABRA2 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6075043-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-06-13 | — | — | US | disclosed |