Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 4/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | TK2 | O00142 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443086 | 0.94 | RNASE1 (0.31) | RNASE1TK1 | |
| SCHEMBL6756344 | 0.79 | RNASE1 (0.37) | RNASE1TK1TK2 | |
| SCHEMBL7863893 | 0.78 | RNASE1 (0.37) | RNASE1TK1TK2 | |
| SCHEMBL1706308 | 0.77 | RNASE1 (0.39) | RNASE1TK1TK2 | |
| SCHEMBL7640426 | 0.76 | RNASE1 (0.39) | RNASE1TK1TK2 | |
| SCHEMBL7973950 | 0.74 | TOP2A (0.36) | RNASE1TK1TERTTK2 | |
| SCHEMBL6753657 | 0.74 | TK1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL5954363 | 0.72 | TK2 (0.33) | RNASE1TK1TK2 | |
| SCHEMBL6301637 | 0.71 | RNASE1 (0.37) | RNASE1TK1TK2 | |
| SCHEMBL6443084 | 0.71 | TOP2A (0.36) | RNASE1TK1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086116-A1 | COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-2000059549-A1 | ANTISENSE OLIGONUCLEOTIDE COMPOSITIONS AND METHODS FOR THE MODULATION OF JNK PROTEINS | ISIS PHARMACEUTICALS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| WO-1999060010-A1 | COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |