Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 4/20 | 0.37 |
| ▸ | TK2 | O00142 | 9/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197887 | 0.90 | PYGM (0.38) | TK1TK2 | |
| SCHEMBL6756343 | 0.88 | RNASE1 (0.36) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL9755149 | 0.86 | RNASE1 (0.39) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL6753651 | 0.83 | RNASE1 (0.35) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL8370048 | 0.82 | RNASE1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL6474433 | 0.82 | TOP2A (0.33) | RNASE1TK1TK2 | |
| SCHEMBL29834215 | 0.81 | RNASE1 (0.37) | RNASE1TK1TK2 | |
| SCHEMBL29834214 | 0.81 | RNASE1 (0.37) | RNASE1TK1TK2 | |
| SCHEMBL9064864 | 0.80 | RNASE1 (0.38) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL17080336 | 0.79 | TK1 (0.38) | RNASE1TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6914148-B2 | Guanidinium functionalized intermediates | ISIS PHARMACEUTICALS, INC. (US) | 2005-07-05 | — | — | US | disclosed |