Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.49 |
| ▸ | PARN | O95453 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7987663 | 0.99 | CNOT7 (0.48) | CNOT7PARNPNPALDH1A1SMN1; SMN2 | |
| SCHEMBL7991568 | 0.92 | SMN1; SMN2 (0.45) | CNOT7PARNPNPSMN1; SMN2ADORA2A | |
| SCHEMBL7974418 | 0.90 | CNOT7 (0.39) | CNOT7PARNPNPALDH1A1SMN1; SMN2 | |
| SCHEMBL7984427 | 0.90 | HPGD (0.44) | CNOT7PARNPNPALDH1A1SMN1; SMN2 | |
| SCHEMBL7988586 | 0.90 | CNOT7 (0.50) | CNOT7PARNPNPALDH1A1SMN1; SMN2 | |
| SCHEMBL7975271 | 0.90 | CNOT7 (0.56) | CNOT7PARNPNPALDH1A1SMN1; SMN2 | |
| SCHEMBL7985302 | 0.89 | ROCK2 (0.41) | CNOT7PARNPNPADORA2A | |
| SCHEMBL7991561 | 0.89 | HPGD (0.43) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7974015 | 0.89 | PARN (0.49) | CNOT7PARNPNPALDH1A1SMN1; SMN2 | |
| SCHEMBL7986359 | 0.89 | CNOT7 (0.52) | CNOT7PARNPNPALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |