SCHEMBL7974028

SCHEMBL7974028

Cc1ccc2[c]c(Cl)oc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.37
NOS1 P29475 2/20 0.36
PSMB8 P28062 1/20 0.36
KEAP1 Q14145 1/20 0.36
NOS3 P29474 1/20 0.36
NOS2 P35228 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
FBP1 P09467 2/20 0.35
ALDH1A1 P00352 4/20 0.34
HPGD P15428 3/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
MAOB P27338 2/20 0.33
ACHE P22303 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974023 0.83 NOS1 (0.40) HSD17B10NOS1PSMB8KEAP1NOS3
SCHEMBL4460823 0.71 AHR (0.38) HSD17B10PSMB8KDM4EMAPTALDH1A1
SCHEMBL7976280 0.71 AHR (0.39) PSMB8KDM4EALDH1A1HPGDLMNA
SCHEMBL25720298 0.67 AHR (0.62) HSD17B10KDM4EMAPTALDH1A1HPGD
SCHEMBL24727144 0.66 TTR (0.47) HSD17B10MAPTALDH1A1HPGDMAOB
SCHEMBL9813983 0.65 PSMB8 (0.38) PSMB8ALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL11025889 0.65 CYP3A4 (0.37) KDM4EALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL11028225 0.65 CYP3A4 (0.37) KDM4EALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL144391 0.64
SCHEMBL11026596 0.64 CYP2A6 (0.43) HSD17B10NOS1NOS3NOS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed