SCHEMBL7976280

SCHEMBL7976280

Cc1[c]c2ccc(Cl)cc2o1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.39
MCL1 Q07820 2/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PSMB8 P28062 2/20 0.36
MAOB P27338 1/20 0.36
PIK3CG P48736 1/20 0.36
NPC1 O15118 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976274 0.86 LMNA (0.40) AHRMCL1KDM4EALDH1A1LMNA
SCHEMBL7974028 0.71 HSD17B10 (0.37) KDM4EALDH1A1LMNAHPGDNFKB1
SCHEMBL167920 0.64
SCHEMBL8155015 0.64 CA12 (0.50) AHRMCL1KDM4EALDH1A1LMNA
SCHEMBL12329693 0.63 ALDH1A1 (0.64) MCL1KDM4EALDH1A1LMNAHPGD
SCHEMBL22737968 0.62 AHR (0.78) AHRMCL1KDM4EALDH1A1LMNA
Bromide SCHEMBL27681143 0.62 TP53 (0.52) ALDH1A1TP53CYP3A4
Fluoride SCHEMBL9348251 0.62 TP53 (0.52) ALDH1A1TP53CYP3A4
Ammonia Solution, Strong SCHEMBL10704776 0.62 TP53 (0.52) ALDH1A1TP53CYP3A4
SCHEMBL2057188 0.62 AHR (0.33) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed