SCHEMBL7974031

SCHEMBL7974031

Cc1cc(Cl)c2o[c]nc2c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NUDT1 P36639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976059 0.80 NUDT1 (0.44) NPC1RAB9ANUDT1
SCHEMBL10866617 0.80 AHR (0.33)
SCHEMBL7976451 0.74 ACHE (0.41)
SCHEMBL940307 0.68 PSMB8 (0.41)
SCHEMBL24758507 0.67 NUDT1 (0.43) NPC1RAB9ANUDT1
SCHEMBL18645373 0.64 NUDT1 (0.68) NPC1RAB9ANUDT1
SCHEMBL938963 0.64 NPC1 (0.42) NPC1RAB9A
SCHEMBL5331382 0.63 AHR (0.36) NPC1RAB9A
SCHEMBL7976178 0.61 SMN1; SMN2 (0.31)
SCHEMBL18267352 0.61 HTT (0.36) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed