SCHEMBL7976451

SCHEMBL7976451

COc1cc(C)cc2n[c]oc12

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.41
ERN1 O75460 1/20 0.32
ALOX5 P09917 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976059 0.77 NUDT1 (0.44) ALDH1A1SMN1; SMN2
SCHEMBL11228160 0.68 MTNR1A (0.34) ALDH1A1SMN1; SMN2
SCHEMBL18645376 0.67 NUDT1 (0.64) ACHEALOX5ALDH1A1
SCHEMBL7978744 0.64 ACHE (0.41) ACHEERN1ALDH1A1SMN1; SMN2
SCHEMBL29108064 0.63 HTR2A (0.36)
SCHEMBL4860937 0.63 ACHE (0.48) ACHEERN1ALDH1A1SMN1; SMN2
SCHEMBL2611542 0.61 ACHE (0.65) ACHEERN1ALDH1A1SMN1; SMN2
SCHEMBL6883393 0.61 ACHE (0.56) ACHEERN1ALDH1A1SMN1; SMN2
SCHEMBL14197696 0.60 ACHE (0.45) ACHEERN1ALDH1A1SMN1; SMN2
SCHEMBL15424071 0.60 ACHE (0.62) ACHEERN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed