Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985419 | 0.89 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDACP1 | |
| SCHEMBL7975265 | 0.87 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7987219 | 0.86 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDPOLB | |
| SCHEMBL7984786 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDPOLB | |
| SCHEMBL7991402 | 0.85 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2KMT2AHPGDMAPK1 | |
| SCHEMBL7984453 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AHPGDADORA3 | |
| SCHEMBL7974083 | 0.81 | ACP1 (0.43) | ALDH1A1SMN1; SMN2KMT2AACP1POLB | |
| SCHEMBL7986518 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7984716 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDPOLB | |
| SCHEMBL7988662 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |