Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986753 | 0.93 | TNKS (0.43) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7991414 | 0.92 | GRIA1 (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7988742 | 0.90 | LMNA (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7985420 | 0.89 | TP53 (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7985116 | 0.89 | HPGD (0.44) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7984677 | 0.88 | TP53 (0.41) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7974198 | 0.88 | LMNA (0.41) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7973916 | 0.88 | LMNA (0.43) | ALDH1A1SMN1; SMN2KMT2ALMNATP53 | |
| SCHEMBL7984786 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KMT2ATP53POLB | |
| SCHEMBL7974079 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |