Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985428 | 0.89 | SMN1; SMN2 (0.41) | ACP1PARNCNOT7ALDH1A1MEN1 | |
| SCHEMBL7975271 | 0.87 | CNOT7 (0.56) | PARNCNOT7ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7984791 | 0.86 | SMN1; SMN2 (0.45) | PARNCNOT7ALDH1A1MEN1KMT2A | |
| SCHEMBL7987224 | 0.86 | LMNA (0.44) | PARNCNOT7ALDH1A1MEN1KMT2A | |
| SCHEMBL7991406 | 0.85 | CNOT7 (0.49) | ACP1PARNCNOT7ALDH1A1MEN1 | |
| SCHEMBL7984461 | 0.82 | CNOT7 (0.52) | ACP1PARNCNOT7ALDH1A1KMT2A | |
| SCHEMBL7984720 | 0.81 | CNOT7 (0.48) | ACP1PARNCNOT7ALDH1A1LMNA | |
| SCHEMBL7974079 | 0.81 | ALDH1A1 (0.47) | ACP1ALDH1A1MEN1KMT2AROCK2 | |
| SCHEMBL7986522 | 0.81 | CNOT7 (0.48) | ACP1PARNCNOT7ALDH1A1MEN1 | |
| SCHEMBL7988669 | 0.81 | PARN (0.48) | ACP1PARNCNOT7ALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |