Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | AANAT | Q16613 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976825 | 0.90 | SMN1; SMN2 (0.71) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1850284 | 0.89 | LMNA (0.60) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7970577 | 0.86 | MEN1 (0.68) | LMNAAANATALDH1A1GAAMAPT | |
| SCHEMBL7972279 | 0.86 | SMN1; SMN2 (0.66) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1849735 | 0.86 | LMNA (0.65) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10069200 | 0.86 | AANAT (0.77) | LMNAAANATALDH1A1PKMKMT2A | |
| SCHEMBL7972207 | 0.84 | LMNA (0.67) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10272692 | 0.84 | MTNR1A (0.64) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7973858 | 0.83 | LMNA (0.62) | LMNAAANATALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6029594 | 0.83 | LMNA (0.62) | LMNAAANATALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |