Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | BUB1 | O43683 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991770 | 0.95 | HTR2C (0.39) | HTR2CSLC6A4BUB1GAAPKM | |
| SCHEMBL7992102 | 0.91 | HTR2C (0.41) | HTR2CSLC6A4BUB1GAAPKM | |
| SCHEMBL7987776 | 0.84 | KDM4E (0.41) | HTR2CSLC6A4GAAPKMTSHR | |
| SCHEMBL8056336 | 0.84 | PKM (0.36) | HTR2CSLC6A4GAAPKMTSHR | |
| SCHEMBL7984483 | 0.83 | TLR7 (0.43) | GAAPKMTSHRP2RX7 | |
| SCHEMBL7987693 | 0.82 | TDP1 (0.34) | HTR2CSLC6A4BUB1GAAAAK1 | |
| SCHEMBL7991771 | 0.82 | KMT2A (0.39) | HTR2CSLC6A4BUB1MCL1GLS | |
| SCHEMBL7974052 | 0.82 | KDM4E (0.42) | HTR2CSLC6A4 | |
| SCHEMBL7985807 | 0.81 | CA1 (0.46) | — | |
| SCHEMBL7984765 | 0.81 | GRM2 (0.36) | BUB1AAK1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |