Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988995 | 0.92 | NR1H4 (0.38) | AAK1BUB1CACNA1H | |
| SCHEMBL7984765 | 0.92 | GRM2 (0.36) | ALDH1A1LMNAAAK1KMT2ABUB1 | |
| SCHEMBL7992102 | 0.91 | HTR2C (0.41) | ALDH1A1L3MBTL1KMT2ABUB1KDM4E | |
| SCHEMBL7974052 | 0.87 | KDM4E (0.42) | SMN1; SMN2TP53POLBHTTL3MBTL1 | |
| SCHEMBL7974433 | 0.84 | TP53 (0.40) | TDP1NPC1RAB9ATP53KMT2A | |
| SCHEMBL7989013 | 0.83 | TP53 (0.38) | ALDH1A1LMNATP53L3MBTL1KMT2A | |
| SCHEMBL7991771 | 0.83 | KMT2A (0.39) | ALDH1A1LMNAKMT2ABUB1KDM4E | |
| SCHEMBL7974264 | 0.82 | HTR2C (0.40) | AAK1BUB1GAAHTR2CSLC6A4 | |
| SCHEMBL7987776 | 0.81 | KDM4E (0.41) | TDP1ALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL7991770 | 0.81 | HTR2C (0.39) | AAK1BUB1GAAHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |