Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992533 | 0.95 | GLS (0.38) | KMT2AGLSBUB1P2RX3HTR2C | |
| SCHEMBL7992102 | 0.91 | HTR2C (0.41) | KMT2AGLSBUB1HTR2CSLC6A4 | |
| SCHEMBL7989013 | 0.83 | TP53 (0.38) | KMT2ABUB1ALDH1A1KDM4EMCL1 | |
| SCHEMBL7987693 | 0.83 | TDP1 (0.34) | KMT2ABUB1HTR2CSLC6A4ALDH1A1 | |
| SCHEMBL7974052 | 0.83 | KDM4E (0.42) | HTR2CSLC6A4KDM4EMAPT | |
| SCHEMBL7974433 | 0.82 | TP53 (0.40) | KMT2AMAPTAURKARPS6KB1 | |
| SCHEMBL7988995 | 0.82 | NR1H4 (0.38) | BUB1 | |
| SCHEMBL7984765 | 0.82 | GRM2 (0.36) | KMT2ABUB1ALDH1A1KDM4ELMNA | |
| SCHEMBL7974264 | 0.82 | HTR2C (0.40) | GLSBUB1HTR2CSLC6A4MCL1 | |
| SCHEMBL7987776 | 0.81 | KDM4E (0.41) | KMT2AHTR2CSLC6A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |