Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | PARN | O95453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988887 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAPOLBMAPTTP53 | |
| SCHEMBL7987439 | 0.83 | CNOT7 (0.43) | SMN1; SMN2LMNAMAPTHTTTP53 | |
| SCHEMBL7984380 | 0.82 | CYP11B1 (0.40) | SMN1; SMN2LMNAMAPTHTTTSHR | |
| SCHEMBL7974269 | 0.82 | TNF (0.44) | TNFSMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL7974262 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2LMNAPOLBMAPTHTT | |
| SCHEMBL7984442 | 0.78 | LMNA (0.42) | LMNAPOLBTP53MEN1KMT2A | |
| SCHEMBL7987963 | 0.78 | CNOT7 (0.38) | SMN1; SMN2HPGDALDH1A1PARNCNOT7 | |
| SCHEMBL7975254 | 0.77 | CNOT7 (0.55) | SMN1; SMN2POLBKMT2AHPGDALDH1A1 | |
| SCHEMBL7984530 | 0.75 | HPGD (0.46) | SMN1; SMN2HTTMEN1KMT2AHPGD | |
| SCHEMBL7988132 | 0.75 | CNOT7 (0.44) | SMN1; SMN2LMNAHPGDALDH1A1PARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |