Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984380 | 0.88 | CYP11B1 (0.40) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7985523 | 0.85 | TDP1 (0.39) | CNOT7PARNHPGDALDH1A1 | |
| SCHEMBL7988132 | 0.83 | CNOT7 (0.44) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7987439 | 0.82 | CNOT7 (0.43) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7987957 | 0.81 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7987444 | 0.81 | PARN (0.42) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7975254 | 0.81 | CNOT7 (0.55) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7974262 | 0.81 | ALDH1A1 (0.45) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7985247 | 0.80 | HSP90AA1 (0.45) | SMN1; SMN2 | |
| SCHEMBL7984530 | 0.79 | HPGD (0.46) | CNOT7PARNHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |