Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985551 | 0.90 | HPGD (0.55) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7984437 | 0.87 | HPGD (0.44) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL22800974 | 0.85 | PNP (0.47) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7985634 | 0.85 | SMN1; SMN2 (0.57) | HPGDPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7988775 | 0.84 | HPGD (0.43) | HPGDLMNATP53POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7987615 | 0.84 | SMN1; SMN2 (0.56) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| Hydrochloric Acid SCHEMBL7984391 | 0.84 | HPGD (0.42) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7974302 | 0.83 | SMN1; SMN2 (0.45) | HPGDPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7974297 | 0.82 | LMNA (0.41) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7988531 | 0.81 | ALDH1A1 (0.44) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |