Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975136 | 0.88 | HPGD (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDHTT | |
| SCHEMBL7988953 | 0.88 | HPGD (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDTYMS | |
| SCHEMBL7985634 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KMT2AHPGDHCAR2 | |
| Hydrochloric Acid SCHEMBL7987615 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDHCAR2 | |
| SCHEMBL7988531 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDHCAR2 | |
| SCHEMBL7984524 | 0.86 | HPGD (0.52) | SMN1; SMN2ALDH1A1KMT2AHPGDTYMS | |
| SCHEMBL7985636 | 0.85 | ABCC8 (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDBRD4 | |
| SCHEMBL7985510 | 0.83 | HPGD (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDTYMS | |
| SCHEMBL7974294 | 0.83 | HPGD (0.43) | SMN1; SMN2ALDH1A1KMT2AHPGDHCAR2 | |
| SCHEMBL7988672 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |