Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 2/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985551 | 0.91 | HPGD (0.55) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7988775 | 0.88 | HPGD (0.43) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7974294 | 0.87 | HPGD (0.43) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7988878 | 0.87 | SMN1; SMN2 (0.46) | HPGDLMNATP53ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7984391 | 0.87 | HPGD (0.42) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL22800974 | 0.83 | PNP (0.47) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7975251 | 0.83 | SMN1; SMN2 (0.60) | HPGDTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL7987219 | 0.81 | ALDH1A1 (0.45) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7973916 | 0.81 | LMNA (0.43) | HPGDLMNATP53POLBALDH1A1 | |
| SCHEMBL7984442 | 0.81 | LMNA (0.42) | HPGDLMNATP53POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |