Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | PDE5A | O76074 | 3/20 | 0.37 |
| ▸ | PDE1A | P54750 | 3/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985554 | 0.91 | SMN1; SMN2 (0.41) | LMNATP53POLBADORA2AADORA1 | |
| SCHEMBL7984440 | 0.87 | PDE4A (0.40) | LMNATP53POLBPDE4APDE4B | |
| SCHEMBL7985637 | 0.84 | SMN1; SMN2 (0.43) | POLBADORA2AALDH1A1PKMKMT2A | |
| SCHEMBL7988782 | 0.84 | PDE4A (0.43) | LMNATP53POLBPDE4APDE4B | |
| Hydrochloric Acid SCHEMBL7987616 | 0.83 | SMN1; SMN2 (0.42) | POLBADORA2AALDH1A1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL7984394 | 0.83 | PDE4A (0.42) | LMNATP53POLBPDE4APDE4B | |
| SCHEMBL7974304 | 0.82 | MET (0.44) | TAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7988533 | 0.81 | TAAR1 (0.43) | TAAR1L3MBTL1HSD17B13PPARG | |
| SCHEMBL7987222 | 0.80 | PDE4A (0.49) | LMNATP53POLBPDE4APDE4B | |
| SCHEMBL7973917 | 0.80 | LMNA (0.40) | LMNATP53POLBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |