Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 2/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988957 | 0.89 | MET (0.45) | METCYP11B2CYP11B1SMN1; SMN2HTT | |
| SCHEMBL7975137 | 0.88 | LMNA (0.42) | METTAAR1CYP11B2CYP11B1SMN1; SMN2 | |
| SCHEMBL7985637 | 0.88 | SMN1; SMN2 (0.43) | CYP11B2CYP11B1SMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7987616 | 0.86 | SMN1; SMN2 (0.42) | CYP11B2CYP11B1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7988533 | 0.86 | TAAR1 (0.43) | TAAR1CYP11B2CYP11B1MAOB | |
| SCHEMBL7984526 | 0.85 | MET (0.46) | METCYP11B2CYP11B1SMN1; SMN2HTT | |
| SCHEMBL7985639 | 0.85 | ABCC8 (0.44) | METCYP11B2CYP11B1 | |
| SCHEMBL7985513 | 0.82 | MET (0.43) | METCYP11B2CYP11B1SMN1; SMN2HTT | |
| SCHEMBL7974295 | 0.82 | LMNA (0.40) | TAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7988674 | 0.81 | SMN1; SMN2 (0.43) | TAAR1CYP11B2CYP11B1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |