Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGAV | P06756 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPR3 | P17342 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | UBE2B | P63146 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448493 | 1.00 | ITGB3 (0.43) | ITGB3ITGAVITGA2BSYKNPR3 | |
| SCHEMBL7976545 | 0.91 | ITGB3 (0.52) | ITGB3ITGAVITGA2BCTSKL3MBTL1 | |
| SCHEMBL7451864 | 0.91 | ITGB3 (0.52) | ITGB3ITGAVITGA2BCTSKL3MBTL1 | |
| SCHEMBL7456394 | 0.79 | SYK (0.53) | ITGB3ITGAVITGA2BSYKCTSK | |
| SCHEMBL7456386 | 0.79 | SYK (0.53) | ITGB3ITGAVITGA2BSYKCTSK | |
| SCHEMBL7962795 | 0.77 | SYK (0.51) | ITGB3ITGAVITGA2BSYKCTSK | |
| SCHEMBL7455995 | 0.77 | SYK (0.51) | ITGB3ITGAVITGA2BSYKCTSK | |
| SCHEMBL7962798 | 0.77 | SYK (0.51) | ITGB3ITGAVITGA2BSYKCTSK | |
| SCHEMBL7450308 | 0.77 | HPGDS (0.47) | ITGB3ITGAVITGA2BSYKCTSL | |
| SCHEMBL7450313 | 0.76 | SYK (0.49) | ITGB3ITGAVITGA2BSYKCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274620-B1 | 2-BENZENESULFONYLAMINO-3-((5-BROMO-THIOPHENE-2-CARBONYL)-AMINO )PROPIONIC ACID-TERT-BUTYL ESTERS AS ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; OSTEOPOROSIS, RESTENOSIS, AND OCULAR NEOVASCULARIZATION | BIOCHEM PHARMA INC. (CA) | 2001-08-14 | — | — | US | disclosed |