Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633308 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BCHRM1ROCK2ACHE | |
| SCHEMBL26668519 | 0.77 | ITGB3 (0.67) | ITGB3ITGA2BCHRM1ROCK2ACHE | |
| SCHEMBL7974335 | 0.77 | ITGB3 (0.60) | ITGB3ITGA2BCHRM1ROCK2ACHE | |
| SCHEMBL27647235 | 0.76 | CYP2C19 (0.46) | NPC1 | |
| SCHEMBL11815953 | 0.74 | ITGB3 (0.61) | ITGB3ITGA2BCHRM1L3MBTL1 | |
| SCHEMBL1416028 | 0.74 | ALDH1A1 (0.45) | NPC1RAB9A | |
| SCHEMBL6767344 | 0.73 | ACKR3 (0.53) | CHRM3 | |
| SCHEMBL17594622 | 0.72 | NPC1 (0.52) | NPC1 | |
| SCHEMBL3982704 | 0.72 | TSHR (0.46) | MAOBNPC1RAB9AL3MBTL1 | |
| SCHEMBL28037255 | 0.72 | MAOB (0.45) | MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |