Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26668519 | 0.90 | ITGB3 (0.67) | ITGB3ITGA2BROCK2CHRM1ACHE | |
| SCHEMBL3039617 | 0.85 | SMYD3 (0.53) | CHRM1CHRM4 | |
| SCHEMBL4633308 | 0.85 | ITGB3 (0.74) | ITGB3ITGA2BROCK2CHRM1ACHE | |
| SCHEMBL3039855 | 0.77 | SMYD3 (0.50) | — | |
| SCHEMBL7974331 | 0.77 | ITGB3 (0.53) | ITGB3ITGA2BROCK2CHRM1ACHE | |
| SCHEMBL2555567 | 0.76 | ITGB3 (0.62) | ITGB3ITGA2BCHRM1ACHE | |
| SCHEMBL10724023 | 0.73 | LDLR (0.62) | ACHE | |
| SCHEMBL8393574 | 0.73 | ACHE (0.69) | ITGB3ITGA2BACHECHRM4 | |
| SCHEMBL27627004 | 0.73 | MAPK14 (0.52) | — | |
| SCHEMBL1099357 | 0.72 | HDAC4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |