Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391438 | 0.93 | ACHE (0.66) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL8393679 | 0.93 | ACHE (0.66) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL25970123 | 0.92 | ACHE (0.61) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL8396478 | 0.92 | SMN1; SMN2 (0.68) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL8395193 | 0.92 | SMN1; SMN2 (0.68) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL1927647 | 0.90 | CHRM4 (0.64) | ACHESMN1; SMN2RAB9ACHRM4 | |
| SCHEMBL8391764 | 0.90 | RAB9A (0.58) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL4633308 | 0.89 | ITGB3 (0.74) | ACHESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL1927379 | 0.86 | ITGB3 (0.60) | ACHEITGB3ITGA2BCHRM4 | |
| SCHEMBL8395564 | 0.83 | SMN1; SMN2 (0.58) | ACHESMN1; SMN2ALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |