Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961151 | 0.88 | HRH4 (0.39) | HRH4HRH3 | |
| SCHEMBL7977425 | 0.88 | FAAH (0.46) | HRH4HRH3LMNA | |
| SCHEMBL7974350 | 0.88 | NPC1 (0.46) | HRH3 | |
| SCHEMBL6970271 | 0.86 | HRH4 (0.44) | HRH4HRH3KMT2AMEN1LMNA | |
| SCHEMBL7961352 | 0.85 | NAAA (0.43) | — | |
| SCHEMBL7971184 | 0.84 | EPHX1 (0.43) | KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL7973065 | 0.83 | NPC1 (0.49) | — | |
| SCHEMBL7989175 | 0.81 | FAAH (0.45) | KMT2AMEN1LMNA | |
| SCHEMBL6973817 | 0.77 | POLB (0.53) | KMT2AMEN1LMNACYP2C19POLB | |
| SCHEMBL7977081 | 0.77 | HRH3 (0.49) | HRH4HRH3KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | disclosed |
| US-5750560-A | ANTICOAGULANTS; FREE RADICAL SCAVENGERS; CARDIOVASCULAR, GASTROINTESTINAL, NERVOUS SYSTEM AND RESPIRATORY SYSTEM DISORDERS | LABORATOIRES DE THERAPEUTIQUE MODERNE (FR) | 1998-05-12 | — | — | US | disclosed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5559113-A | ANTAGONISTS TO HISTAMINE H3 RECEPTORS, SEDATIVES, ANTICONVULSANTS, ANTIULCER AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | 1996-09-24 | — | — | US | disclosed |