Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968612 | 0.86 | ROCK2 (0.47) | HRH4HRH3LMNACYP2C9CYP2C19 | |
| SCHEMBL7974343 | 0.86 | HRH4 (0.51) | HRH4HRH3KMT2AMEN1LMNA | |
| SCHEMBL6972584 | 0.84 | L3MBTL1 (0.43) | HRH4HRH3KMT2ALMNAPOLB | |
| SCHEMBL6974399 | 0.84 | ESR1 (0.42) | HRH4HRH3KMT2AMEN1LMNA | |
| SCHEMBL6965330 | 0.84 | ESR1 (0.42) | HRH4HRH3KMT2AMEN1LMNA | |
| SCHEMBL6961677 | 0.81 | MEN1 (0.56) | KMT2AMEN1LMNACYP2C9CYP2C19 | |
| SCHEMBL6960067 | 0.81 | MEN1 (0.56) | KMT2AMEN1LMNACYP2C9CYP2C19 | |
| SCHEMBL6970199 | 0.79 | RAB9A (0.40) | HRH4HRH3LMNAPOLBKDM4E | |
| SCHEMBL9028109 | 0.79 | PLAAT3 (0.39) | KMT2AMEN1LMNACYP2C9CYP2C19 | |
| SCHEMBL7989175 | 0.79 | FAAH (0.45) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |