SCHEMBL7974375

SCHEMBL7974375

COCCOCCOCCSc1cccc(COC(Cl)c2cccc(SCCOCCOCCOC)c2C)c1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977537 0.79 MAPK1 (0.35) LMNAGAA
SCHEMBL7963854 0.76 PDCD1 (0.37) LMNAGAA
SCHEMBL7974379 0.74 ALDH1A1 (0.34) LMNAGAA
SCHEMBL7974431 0.65 SMN1; SMN2 (0.55) LMNA
SCHEMBL7974426 0.65 SMN1; SMN2 (0.55) LMNA
SCHEMBL20706921 0.61 HTR7 (0.38) LMNAGAA
SCHEMBL8917405 0.61 MAP2K7 (0.30)
SCHEMBL8915012 0.61 MAP2K7 (0.30)
SCHEMBL8914444 0.60 MAPK1 (0.36) LMNAGAA
SCHEMBL21331194 0.60 ALDH1A1 (0.39) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001034573-A1 COMPOUNDS ASTRAZENECA AB (SE) 2001-05-17 WO disclosed