Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974379 | 0.94 | ALDH1A1 (0.34) | MAPK1ALDH1A1PKMHSD17B10PTGS2 | |
| SCHEMBL7963854 | 0.86 | PDCD1 (0.37) | MAPK1ALDH1A1PKMHSD17B10PTGS2 | |
| SCHEMBL7974375 | 0.79 | LMNA (0.33) | LMNAGAA | |
| SCHEMBL7994038 | 0.78 | HTR7 (0.33) | — | |
| SCHEMBL7977434 | 0.75 | L3MBTL1 (0.43) | ALDH1A1KDM4ETDP1POLBLMNA | |
| SCHEMBL7974426 | 0.72 | SMN1; SMN2 (0.55) | ALDH1A1KMT2AHPGDHTTLMNA | |
| SCHEMBL7974431 | 0.72 | SMN1; SMN2 (0.55) | ALDH1A1KMT2AHPGDHTTLMNA | |
| SCHEMBL7963994 | 0.70 | LMNA (0.50) | MAPK1ALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL20706921 | 0.69 | HTR7 (0.38) | MAPK1ALDH1A1PTGS2KDM4ETDP1 | |
| SCHEMBL8915012 | 0.69 | MAP2K7 (0.30) | MAP2K7CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |