Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971449 | 0.89 | MAOB (0.44) | MAOBPPARDHPGDDDB1CRBN | |
| SCHEMBL7974878 | 0.87 | HPGD (0.41) | MAOBHPGDDRD2DRD4 | |
| SCHEMBL7974787 | 0.86 | TEAD1 (0.45) | MAOBPPARDHPGDDRD2DRD4 | |
| SCHEMBL7974650 | 0.84 | MGAT2 (0.42) | MAOBHPGDNFE2L2 | |
| SCHEMBL7961502 | 0.83 | MAOB (0.40) | MAOBHPGDNFE2L2 | |
| SCHEMBL7974962 | 0.83 | MAOB (0.40) | MAOBHPGDNFE2L2 | |
| SCHEMBL7971414 | 0.82 | PPARD (0.43) | MAOBPPARDHPGDITGB3ITGA2B | |
| SCHEMBL7974454 | 0.81 | HRH3 (0.43) | MAOBPPARDHPGDNFE2L2 | |
| SCHEMBL7961113 | 0.81 | HPGD (0.42) | MAOBPPARDHPGDITGB3ITGA2B | |
| SCHEMBL7974340 | 0.80 | CHRNB2 (0.44) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |