Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971414 | 0.92 | PPARD (0.43) | TEAD1TEAD3MAOBNFE2L2HPGD | |
| SCHEMBL7971449 | 0.92 | MAOB (0.44) | RAB9AMAOBNFE2L2HPGDPPARD | |
| SCHEMBL7974650 | 0.89 | MGAT2 (0.42) | MAOBNFE2L2HPGD | |
| SCHEMBL7974962 | 0.88 | MAOB (0.40) | NPC1RAB9AMAOBNFE2L2HPGD | |
| SCHEMBL7961502 | 0.88 | MAOB (0.40) | MAOBNFE2L2HPGD | |
| SCHEMBL7974477 | 0.87 | PKM (0.47) | NPC1RAB9A | |
| SCHEMBL7974398 | 0.86 | MAOB (0.39) | MAOBDRD2DRD4NFE2L2HPGD | |
| SCHEMBL7974454 | 0.86 | HRH3 (0.43) | MAOBNFE2L2HPGDPPARD | |
| SCHEMBL7961113 | 0.86 | HPGD (0.42) | TEAD1TEAD3MAOBNFE2L2HPGD | |
| SCHEMBL7974340 | 0.85 | CHRNB2 (0.44) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |