Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 9/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971449 | 0.92 | MAOB (0.44) | NFE2L2MAOBHPGDKDM4EL3MBTL1 | |
| SCHEMBL7974787 | 0.89 | TEAD1 (0.45) | NFE2L2MAOBHPGD | |
| SCHEMBL7961502 | 0.88 | MAOB (0.40) | NFE2L2MAOBHPGDALDH1A1KMT2A | |
| SCHEMBL7974962 | 0.88 | MAOB (0.40) | NFE2L2MAOBHPGDL3MBTL1 | |
| SCHEMBL7971414 | 0.87 | PPARD (0.43) | NFE2L2MAOBHPGDALDH1A1 | |
| SCHEMBL7974454 | 0.86 | HRH3 (0.43) | MGAT2NFE2L2MAOBHPGDALDH1A1 | |
| SCHEMBL7961113 | 0.86 | HPGD (0.42) | NFE2L2MAOBHPGDKMT2AGRM2 | |
| SCHEMBL7974477 | 0.85 | PKM (0.47) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7974398 | 0.84 | MAOB (0.39) | NFE2L2MAOBHPGD | |
| SCHEMBL7974701 | 0.84 | L3MBTL1 (0.47) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |