Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974398 | 0.87 | MAOB (0.39) | HPGDDRD2DRD4MAOB | |
| SCHEMBL7971449 | 0.82 | MAOB (0.44) | HPGDMAOB | |
| SCHEMBL7974787 | 0.82 | TEAD1 (0.45) | HPGDDRD2DRD4MAOBNPC1 | |
| SCHEMBL7974650 | 0.80 | MGAT2 (0.42) | HPGDSMN1; SMN2MAOBKMT2AMEN1 | |
| SCHEMBL7961502 | 0.79 | MAOB (0.40) | HPGDLMNAMAOBKMT2AMEN1 | |
| SCHEMBL7974962 | 0.79 | MAOB (0.40) | HPGDMAOBNPC1 | |
| SCHEMBL7971414 | 0.78 | PPARD (0.43) | HPGDMAOB | |
| SCHEMBL7974454 | 0.77 | HRH3 (0.43) | HPGDSMN1; SMN2MAOBKMT2AMEN1 | |
| SCHEMBL7961113 | 0.77 | HPGD (0.42) | HPGDMAOBKMT2A | |
| SCHEMBL7974340 | 0.76 | CHRNB2 (0.44) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |