Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991646 | 0.91 | SMN1; SMN2 (0.43) | PIK3CAMTORPIK3CGSMN1; SMN2HSD17B13 | |
| SCHEMBL7988787 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1GAAHPGDCYP11B1 | |
| SCHEMBL7975267 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1GAAHPGDCYP11B1 | |
| SCHEMBL7985565 | 0.90 | HDAC6 (0.40) | PIK3CAMTORPIK3CGSMN1; SMN2GAA | |
| SCHEMBL7985613 | 0.90 | MET (0.46) | PIK3CAMTORPIK3CGHSD17B13HDAC1 | |
| SCHEMBL7984659 | 0.89 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GAAHPGDCYP11B1 | |
| SCHEMBL7974012 | 0.89 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL7991635 | 0.89 | IDO1 (0.37) | PIK3CAMTORPIK3CGHSD17B13HDAC1 | |
| SCHEMBL7974247 | 0.89 | CYP11B1 (0.44) | PIK3CAMTORPIK3CGSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7987662 | 0.88 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1GAAHPGDCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |