SCHEMBL7974412

SCHEMBL7974412

O=C(O)CCC1C=CCC1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
USP2 O75604 1/20 0.49
ALOX15 P16050 1/20 0.49
CHRNB2 P17787 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
CHRNB3 Q05901 1/20 0.40
CHRNA6 Q15825 1/20 0.40
HSD17B10 Q99714 2/20 0.34
LMNA P02545 2/20 0.34
CYP2C9 P11712 1/20 0.34
MEN1 O00255 1/20 0.34
NR1I2 O75469 1/20 0.34
POLB P06746 1/20 0.34
THRB P10828 1/20 0.34
TSHR P16473 1/20 0.34
ACHE P22303 1/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12794411 1.00 ALDH1A1 (0.49) ALDH1A1TDP1USP2ALOX15CHRNB2
SCHEMBL14706726 0.88 ALDH1A1 (0.54) ALDH1A1TDP1USP2ALOX15CHRNB2
SCHEMBL9182928 0.88 ALDH1A1 (0.40) ALDH1A1TDP1USP2ALOX15CHRNB2
SCHEMBL17540730 0.86 ALDH1A1 (0.60) ALDH1A1TDP1USP2ALOX15CHRNB2
Chaulmoogric Acid SCHEMBL560850 0.85 ALDH1A1 (0.63) ALDH1A1TDP1USP2ALOX15HSD17B10
SCHEMBL4558351 0.85 ALDH1A1 (0.63) ALDH1A1TDP1USP2ALOX15HSD17B10
SCHEMBL580439 0.85 ALDH1A1 (0.63) ALDH1A1TDP1USP2ALOX15HSD17B10
SCHEMBL2491883 0.85 ALDH1A1 (0.63) ALDH1A1TDP1USP2ALOX15HSD17B10
SCHEMBL2494531 0.85 ALDH1A1 (0.63) ALDH1A1TDP1USP2ALOX15HSD17B10
Chaulmoogric Acid SCHEMBL560849 0.85 ALDH1A1 (0.63) ALDH1A1TDP1USP2ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513235-B Process for producing diglyceride 帝斯曼知识产权资产管理有限公司 2023-12-01 CN disclosed
CN-109010827-A Chlorambucil-poly-dopamine prodrug nanoparticle antitumor application thereof 上海交通大学 2018-12-18 CN disclosed
US-20100221809-A1 Compositions and Methods for the Isolation of Biologically Active Proteins THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-09-02 US disclosed
US-RE37303-E1 Imidazole compounds and their therapeutic applications INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2001-07-31 US disclosed
US-6008398-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-12-28 US disclosed
US-5919965-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-07-06 US disclosed
EP-0880532-A4 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1999-06-09 EP disclosed
EP-0880532-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1998-12-02 EP disclosed
EP-0804443-A4 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1998-04-29 EP disclosed
US-5708171-A HISTAMINE H3-RECEPTOR ANTAGONIST INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1998-01-13 US disclosed
EP-0804443-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-11-05 EP disclosed
WO-1997028168-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-08-07 WO disclosed
US-5559113-A ANTAGONISTS TO HISTAMINE H3 RECEPTORS, SEDATIVES, ANTICONVULSANTS, ANTIULCER AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE 1996-09-24 US disclosed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100221809-A1 Compositions and Methods for the Isolation of Biologically Active Proteins PLA2G4C, PLA2G4A, PEBP1 ALDH1A1 4847/4885TDP1 3102/4885USP2 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.