Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988732 | 0.92 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDTYMS | |
| SCHEMBL7985297 | 0.91 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AHPGDACP1 | |
| SCHEMBL7984655 | 0.90 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDTYMS | |
| SCHEMBL7984419 | 0.90 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDTP53 | |
| SCHEMBL7988776 | 0.90 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDUSP2 | |
| Hydrochloric Acid SCHEMBL7987658 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDTYMS | |
| SCHEMBL7985609 | 0.89 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDTYMS | |
| SCHEMBL7986518 | 0.88 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDPNP | |
| SCHEMBL7991397 | 0.87 | ABCC8 (0.43) | ALDH1A1SMN1; SMN2KMT2AHPGDPNP | |
| SCHEMBL7984279 | 0.87 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2KMT2AHPGDTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |