Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7987658 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7991564 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7974420 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7988580 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7984419 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7975265 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7985297 | 0.89 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL7991556 | 0.89 | HPGD (0.43) | SMN1; SMN2ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL7974010 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDPNP | |
| SCHEMBL7986351 | 0.89 | KDM4E (0.50) | SMN1; SMN2ALDH1A1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |