Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120642 | 0.89 | HRH4 (0.43) | NAAAHRH4HRH3SMN1; SMN2ASAH1 | |
| SCHEMBL7971225 | 0.81 | HRH3 (0.40) | NAAAHRH4HRH3 | |
| SCHEMBL7976777 | 0.79 | HRH3 (0.38) | NAAAHRH4HRH3 | |
| SCHEMBL9850899 | 0.79 | HRH4 (0.40) | HRH4HRH3 | |
| SCHEMBL18381260 | 0.78 | NPC1 (0.39) | HRH4HRH3 | |
| SCHEMBL7625072 | 0.76 | GPR84 (0.42) | HRH4HRH3 | |
| SCHEMBL7971425 | 0.76 | HRH3 (0.50) | NAAAHRH4HRH3ASAH1EPHX1 | |
| SCHEMBL7971147 | 0.76 | MEN1 (0.43) | HRH4HRH3 | |
| SCHEMBL8524329 | 0.76 | HRH4 (0.41) | HRH4HRH3 | |
| SCHEMBL7977147 | 0.76 | HRH4 (0.38) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | claimed |
| EP-0597088-B1 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2000-12-06 | — | — | EP | claimed |