Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971225 | 0.99 | HRH3 (0.40) | HRH3HRH4HPGDHTR1AHTR1D | |
| SCHEMBL7977147 | 0.93 | HRH4 (0.38) | HRH3HRH4HTR1AHTR1DHTR1B | |
| SCHEMBL9850899 | 0.88 | HRH4 (0.40) | HRH3HRH4 | |
| SCHEMBL7625072 | 0.85 | GPR84 (0.42) | HRH3HRH4HTR1AHTR1DHTR1B | |
| SCHEMBL8524329 | 0.81 | HRH4 (0.41) | HRH3HRH4CDK1CCNB1CCNA2 | |
| SCHEMBL8120642 | 0.80 | HRH4 (0.43) | HRH3HRH4NAAA | |
| SCHEMBL7976815 | 0.80 | DRD2 (0.35) | HRH3HRH4 | |
| SCHEMBL4384996 | 0.80 | HRH4 (0.32) | HRH3HRH4HTR1AHTR1DHTR1B | |
| SCHEMBL7974438 | 0.79 | NAAA (0.46) | HRH3HRH4NAAA | |
| SCHEMBL8115341 | 0.79 | HRH4 (0.34) | HRH3HRH4HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |