Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | DHPS | P49366 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984766 | 0.90 | HPGD (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDDHPS | |
| SCHEMBL7989418 | 0.90 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDDHPS | |
| SCHEMBL7988656 | 0.90 | NPY5R (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL7975265 | 0.90 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL7986324 | 0.89 | HPGD (0.48) | ALDH1A1SMN1; SMN2KMT2AHPGDDHPS | |
| SCHEMBL7988931 | 0.88 | GRIN1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHPGDCYP3A4 | |
| SCHEMBL7974236 | 0.88 | ABCC8 (0.43) | ALDH1A1SMN1; SMN2KMT2AHPGDDHPS | |
| SCHEMBL7985331 | 0.88 | GRIN1 (0.45) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL7974445 | 0.87 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2AHPGDCNOT7 | |
| SCHEMBL7974041 | 0.87 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KMT2AHPGDDHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |