Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974447 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11LMNAPGRCYP3A4 | |
| SCHEMBL7974393 | 0.78 | CYP4F2 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL7972852 | 0.76 | LMNA (0.44) | CYP4F2CYP4A11LMNAPGRCYP3A4 | |
| SCHEMBL7971401 | 0.71 | LMNA (0.40) | LMNAPGRCYP3A4CYP2D6MAPT | |
| SCHEMBL7977404 | 0.64 | MAPT (0.46) | LMNAPGRCYP3A4CYP2D6MAPT | |
| SCHEMBL15661792 | 0.62 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL7972666 | 0.62 | CYP4F2 (0.45) | CYP4F2CYP4A11 | |
| SCHEMBL17378006 | 0.62 | CETP (0.44) | CYP4F2CYP4A11 | |
| SCHEMBL22098378 | 0.61 | CYP4F2 (1.00) | CYP4F2CYP4A11CYP3A4MAPTTDP1 | |
| SCHEMBL22098215 | 0.61 | CYP4F2 (1.00) | CYP4F2CYP4A11CYP3A4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |