Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.39 |
| ▸ | HLCS | P50747 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974714 | 0.92 | MAPT (0.35) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7971395 | 0.79 | ALDH1A1 (0.44) | TDP1CYP3A4ALDH1A1 | |
| SCHEMBL7972650 | 0.75 | — | — | |
| SCHEMBL7974325 | 0.74 | HTR1A (0.48) | TDP1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7974717 | 0.70 | PKM (0.48) | MAPK1HTTALDH1A1 | |
| SCHEMBL7961038 | 0.70 | BRD4 (0.35) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7972852 | 0.69 | LMNA (0.44) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL16128954 | 0.64 | — | — | |
| SCHEMBL11108043 | 0.63 | CYP1A2 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19HLCS | |
| SCHEMBL9614688 | 0.63 | HLCS (0.35) | HLCSBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |