Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974408 | 0.87 | EPHX2 (0.39) | LMNAMAPTTBXA2RMMP2MMP3 | |
| SCHEMBL7961222 | 0.78 | OPRM1 (0.36) | MAOATSHROPRM1OPRL1KCNA3 | |
| SCHEMBL7972852 | 0.76 | LMNA (0.44) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL7974475 | 0.71 | CYP4F2 (0.43) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL7974447 | 0.70 | CYP4F2 (0.43) | LMNACYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL15795307 | 0.67 | SLC6A4 (0.54) | LMNAMAOAHTTOPRM1OPRL1 | |
| SCHEMBL7973063 | 0.67 | MMP2 (0.32) | MMP2MMP3MMP9TSHROPRM1 | |
| SCHEMBL27377646 | 0.66 | HTR2A (0.46) | CYP2D6OPRM1OPRL1 | |
| SCHEMBL31147331 | 0.65 | MEN1 (0.50) | LMNAMAPTCYP2C9MAOAHTT | |
| SCHEMBL7961297 | 0.65 | L3MBTL1 (0.33) | MMP2MMP3MMP9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |