Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 4/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988517 | 0.90 | ABCC8 (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7984930 | 0.90 | ABCC8 (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7987359 | 0.89 | TNKS (0.48) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7987948 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7974236 | 0.89 | ABCC8 (0.43) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7991397 | 0.89 | ABCC8 (0.43) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7985008 | 0.89 | ABCC8 (0.43) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7975265 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL8056958 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS | |
| SCHEMBL7974275 | 0.88 | HPGD (0.43) | SMN1; SMN2ALDH1A1HPGDKMT2ATNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |